12.10pm: Good afternoon. Jamie Jackson will be online from 1pm BST to take part in a live webchat. If you have any questions about this weekend's fixtures in the Premier League, drop them into the comments section below.

After a midweek spent counting goals in everyone's new favourite competition, the Capitol One Cup, we're back to the Premier League.

Manchester United play Arsenal at Old Trafford at 12.45pm on Saturday in the first game of the weekend. Ahead of that fixture, Jamie attended Alex Ferguson's press conference this morning, where the Manchester United manager declared his support for Mark Clattenburg. Arsène Wenger has also spoken to the press. He wants Arsenal fans to give Robin van Persie a respectful reception on his return to the club he captained last season.

Arsenal and Manchester United take top billing, but this weekend's fixtures throw up some other fascinating encounters. Chelsea travel to Swansea; Liverpool host Newcastle; and QPR and Reading, the only clubs in the league without a win, meet at Loftus Road.

Here is the fixture list for the weekend:

Saturday
Manchester United v Arsenal
Fulham v Everton
Norwich v Stoke
Sunderland v Aston Villa
Swansea v Chelsea
Tottenham v Wigan
West Ham v Manchester City

Sunday
QPR v Reading
Liverpool v Newcastle

If you have any questions for Jamie, drop them into the comments section below.

12.36pm: While waiting for Jamie, why not read his report from Roberto Mancini's press conference this morning, where the City manager admitted he had spoken to Monaco about joining them in the summer.

Mancini said: "Last year I was very close with seven, eight teams but I prefer to stay here because I work well here the first three years. Also, if someone thinks we didn't do a good job – we won three trophies in two years and I'm very happy."

1.04pm: Jamie Jackson is in the comments section answering questions.

1.06pm: Creatureofthenight asks: "Do you think Robin van Persie can break Ronaldo's Premier League record of 31 goals this season?"

Jamie replies:

Seven from nine isn't a bad start and Manchester United can't stop scoring at moment (and conceding), so with a fair wind...

1.09pm: Cuncha asks about the starting line-up for Manchester United v Arsenal.

Jamie replies:

Front four for me: Valencia, Rooney, Young; Van Persie

1.15pm: Dragonluck asks: "Would you agree that the overall quality in the league is rather low this season?"

Jamie replies:

It's certainly been entertaining... the defending has been a bit lax but I've seen some brilliant attacking from Man United and Spurs – when they came to Old Trafford. Manchester City have been poor going forward – they're not the side that demolished United at Old Trafford 6-1 about this time last year. Yet.

1.18pm: Cleckers asks: "What do you think of Norwich and Reading's chances this week (and Southampton if Monday's games count)?"

Jamie replies:

Reading have a big chance of beating QPR, though it's difficult to tell what that 7-5 loss to Arsenal will do their squad. Norwich are unbeaten in three, they're at home to Stoke City, so...

1.20pm: Creditcrunched asks: "How do you fancy Newcastle's chances on Sunday given that we've been humped at Anfield every year since some time in the mid-1990s?"

Jamie replies:

Apparently Newcastle 5-1 to beat Liverpool could be worth a ha'penny.

1.23pm: blobbymrblobby asks: "If Liverpool beat Newcastle on Sunday, they'll be level on points. Who do you see finishing higher in the league?"

Jamie replies:

Newcastle, unless Rodgers gets in two strikers who can score. I'd also have Andy Carroll back: it can't hurt to have an option to win games late on.

1.26pm: CavalierDisregard asks: "Who would you pick in goal for Spurs: Friedel or Lloris? I'd go for Lloris. Friedel is still a great keeper, but I feel we need to start bedding in Lloris who I think is one of the best in the world."

Jamie replies:

I'd stay with Brad Friedel until/if he makes a few howlers. I can't work out why AVB did this with his goalkeeping situation, unless he was going to install Lloris instantly. Confusion over any position isn't great for a team, especially the goalkeeper.

1.29pm: labellevue asks: "Do you think the Financial Fair Play rules will make a real difference, or will clubs just get around it by 'connected parties' sponsorship deals or other tricks?"

Jamie replies:

I can't see it making too much difference, in short-term anyway. Not sure how it'll be policed.

1.32pm: MMGALIAS asks: "Do Roberto Mancini's discussions with Monaco epitomise the mercenary culture that is developing in football – and at Manchester City in particular?"

Jamie replies:

Football is a business like any other. Pretty sure that sort of thing has always gone on. What's interesting now is the growing Barcelona connection with the chief executive and director of football now ex-Barca. I'm sure there is a third one out there somewhere who could make it a trio...

1.33pm: CreatureOfTheNight asks: "What's the likelihood that Manchester United may sell Nani in January? Do you think Ferguson's recent criticism of Nani is fair or harsh?"

Jamie replies:

Inconsistency seems to be the main issue regarding why he's not always in the first XI. Fergie's public negative comments on players are rare, so the midweek ones about Nani costing United the tie are intriguing. Looking at SAF's squad you could make a case that he could lose a winger as he has Young, Valencia, Kagawa (who plays wide for Japan).

1.37pm: JahLion asks: "Who is going to get sacked first: Martin O'Neill, Mark Hughes, Nigel Adkins or Arsene Wenger? Wenger and O'Neill are surely far longer odds to get the chop than the other two. Manicini is more likely to be fired than Wenger or O'Neill."

Jamie replies:

Hughes would be my first choice, though Southampton may also be looking around.

1.40pm: campasyoulike asks: "If, as seems likely, Clattenburggate turns out to be a mishearing of "Mikey" as "Monkey" Will Chelsea's embarrassment be sufficient punishment?"

Jamie replies:

Whatever the truth, I'm not sure why they went public with it on Sunday. Why not report to match delegate and let the thing run. Oddly handled, I reckon.

1.45pm: jimmysten asks: "The big game of the week: Fulham v Everton. Two teams who have surprised a few people so far, who do you think will win? Should I keep Jelavic in my fantasy football team?"

Jamie replies:

Everton and yes on Jelavic. If David Moyes can keep the squad fit, Everton have a big chance of top four and Champions League football next season. Marouane Fellaini finally looks a player and at 24 can only improve.

1.49pm: afurby asks: "Will Chelsea's form inevitably fall apart or can they sustain it even though their defence is their weakest link?"

Jamie replies:

I think they could fall off, a little. Like all the teams up there, they are very impressive going forward but a bit dodgy at back. And despite their £50 million man, Chelsea require a goalscoring striker for what is a long season.

1.53pm: Craddockinho makes a point about the goalkeeping situation at Spurs: "Didn't Harry Redknapp want Tim Krul? Presumably because his other keeper was 63 years old. Once the new boss comes in and buys a keeper he is slaughtered in the press, including by 'Arry. Surely it makes sense to replace your key players a moment too early than a moment too late?"

Jamie replies:

Fair comment. Except the incoming guy is France captain, so he would expect to start. It differs to, say, the David de Gea-Anders Lindegaard situation at MUFC.

1.59pm: JahLion asks: "Why do you think Wenger experimented with Gervinho up front this season rather than Walcott? Gervinho has scored a few goals but it just seems bizarre given Walcott's finishing ability, which has been evident for a while now."

Jamie replies:

Good question. Arsene Wenger does not seem to have had too much faith in Theo Walcott but maybe this will change. Be a fair statement if he chose him in attack at Old Trafford tomorrow for Arsenal versus Manchester United.

2.03pm: OttoMaddox asks: "Darren Bent, Theo Walcott, Daniel Sturridge, Demba Ba, Gary Hooper; lots of names are being bandied about but, ignoring unrealistic targets like Klaas Jan Huntelaar, who do you see as the likeliest striking choice for Liverpool in the transfer window?"

Jamie replies:

Why not try and get Darren Bent and Theo Walcott, and recall Andy Carroll, then, with Luis Suarez, Liverpool suddenly have all kinds of options. If they can't get Bent, try Jermain Defoe.

2.05pm: Jamie Jackson has signed off:

Ok folks, thanks very much for your questions. I'm off to write up the Guardian's Manchester United and Manchester City reports for tomorrow's newspaper, before a trip to Upton Park for City's game with West Ham. Cheers.

Thanks for your comments and questions.

Jamie has finished up, but elsewhere on the football site we have Louise Taylor's 10 things to look forward to this weekend blog and Barry Glendenning's selection of penalty shootouts in this week's Joy of Six.