1. Will Manchester City finally lose?
Roberto Mancini's team are unbeaten in their opening 14 games as the whispers begin debating whether the Arsenal Invincibles of 2004 can be emulated. In town are David Moyes's side, who stand sixth, four places and 11 points worse off than the champions. City have not lost at home in the Premier League since a 2-1 reverse on 20 December 2010. The opposition? Everton.
2. Will Chelsea finally score under their new manager?
The weekend's action begins with a humdinger at Upton Park where West Ham United entertain Chelsea in the 12.45pm kick-off. Zero-zero draws in Rafael Benítez's opening two games have hardly helped convince supporters to embrace his brave new world. Another one-pointer or, worse, a defeat, would leave the west London club all but out of the title race a month before Christmas.
3. Will Darren Bent get a chance to impress Harry Redknapp?
The stand-out narratives from this slice of the Premier League soap opera are the attempt of Harry Redknapp to guide QPR to a first victory of the season and Darren Bent's wait to see if he is in Paul Lambert's match-day squad after missing out in Aston Villa's previous two games. A guess is that it will be a no for the latter and a yes for the former: the Hoops could well enjoy a first three points since Stoke City were beaten on last season's penultimate day.
4. Will Carlos Tevez get a start for City?
The Argentinian has been dropped from Roberto Mancini's previous three starting XIs, Wednesday's 2-0 at Wigan Athletic, Sunday's 0-0 at Chelsea and the 1-1 with Real Madrid in the Champions League on 21 November. This despite Tevez scoring twice in the 5-0 victory over Aston Villa in City's previous match. Tevez is currently content with life, though no player, especially a proven match-winner, likes to be left out …
5. Will Anderson be given another start?
Manchester United are at Reading in Saturday's late game after Sir Alex Ferguson's team scraped an unconvincing 1-0 win over West Ham on Wednesday. This featured Anderson being given the start he was promised by the Scot after a match-changing cameo in last Saturday's 3-1 win over Queens Park Rangers when entering as a substitute. Against West Ham the Brazilian was back to his more recognisable muted self. Expect him to be back on the bench at the Madejski Stadium.
6. Liverpool need to start winning
After 14 games the clubs sitting above the five-times European champions include West Bromwich Albion, Stoke City, West Ham and Fulham. Brendan Rodgers' side have 16 points, which is 17 behind the leaders, United, and stand 12th. As Southampton arrive at Anfield on Saturday the question runs whether Liverpool are making sufficient progress under the Northern Irishman.
7. Will Michu last at Swansea City beyond the winter transfer window?
The Spaniard has eight goals in 14 league starts as Michael Laudrup's side head to Arsenal on Saturday. If he scores a 10th during his debut domestic campaign (he also has a League Cup goal) against Arsène Wenger's men, the £2m summer bargain will continue to increase his worth and desirability.
8. Andy Carroll watch
Carroll did score his first goal for West Ham last Sunday but a sole strike in 14 appearances (including two for England) is a dismal return for the on-loan Liverpool forward. It is too early to judge if the Andy Carroll story will one day mirror that of the downfall of Fernando Torres but there are already echoes in the way the Geordie left success at one club (Newcastle United) for failure at another (Liverpool). Against Chelsea the £35m man may share the Upton Park pitch with Torres, the £50m man whose career graph plunged when he left Liverpool for west London.
9. Should Spurs' star man look to leave in January?
Fulham are next up in the Gareth Bale roadshow as the Welshman looks to follow his match-winning display against Liverpool on Wednesday by again running the Tottenham side, and the contest, at Craven Cottage. Bale continues to suggest he has a case for the league's best player and as one of the continent's finest. If so, his development may be best served by leaving for the challenge of playing for a side contesting the title – either here or abroad – rather than in one competing for a Champions League berth.
10. The Wayne Rooney conundrum
Rooney has only three goals in 14 outings for Manchester United this term and he was again becalmed against West Ham at Old Trafford on Wednesday. This may be a result of him occasionally operating at the tip of Ferguson's new diamond shape but the sense is he is yet to click into high gear alongside Robin van Persie, who has 13 in 20 United appearances. At Reading Rooney hopes to start his own goal avalanche.